Morning hand swelling in pregnant women is mostly caused by physiological factors, mainly including hemodilution, changes in endocrine function and dietary changes, but if the hand swelling is serious or accompanied by generalized edema, it is necessary to consider whether there is hypertension during pregnancy or combined with other diseases, such as kidney or liver diseases or rheumatoid arthritis, etc. Physiological factors: 1. Hemodilution: the blood volume of pregnant women increases, and the consumption of protein increases significantly after the fetus increases, which can easily lead to hemodilution and a significant decrease in the protein content of plasma, which in turn causes an increase in intertissue fluid, resulting in swollen hands and eyelids; 2. Endocrine function changes: the hormones secreted by the placenta and the aldosterone secreted by the adrenal glands of pregnant women increase, which can cause water and sodium retention in their bodies The change in diet: if a pregnant woman drinks too much water and consumes too much salt the night before, it can cause water metabolism disorder, which in turn causes morning edema. Pathological factors: 1. Gestational hypertension: this disease can lead to a low discharge and high resistance state of the cardiovascular system of pregnant women, coupled with increased vascular permeability due to endothelial cell activation, which can cause morning edema in pregnant women. At the same time, gestational hypertension can also cause renal pathological changes, that is, plasma protein leakage from the glomerulus to form proteinuria, and a large amount of protein loss in the blood, resulting in a decrease in plasma osmolality in pregnant women, which can cause morning edema, and in serious cases can cause generalized edema; 2, other diseases: if a pregnant woman has morning edema accompanied by facial or leg swelling, kidney and liver diseases should be considered; if a pregnant woman has swollen hands and joint pain, she should be considered as a pregnant woman. If the pregnant woman’s hands are swollen and accompanied by joint pain, rheumatoid arthritis should be considered.