Treatment (a) Lifestyle modification: In patients with obese polycystic ovary syndrome, diet and increased exercise should be controlled to reduce weight and reduce waist circumference, which can increase insulin sensitivity and lower insulin and testosterone levels, thus restoring ovulation and fertility function. In addition, women with PCOS who desire to conceive should undergo adequate health assessment before conception and be given advice on smoking cessation, lifestyle, diet, and appropriate vitamin supplementation (e.g., folic acid). (II) Medication 1. Regulation of menstrual cycle (1) Oral contraceptive pills: for combined estrogen and progestin cycle therapy, commonly used oral contraceptive pills, taken periodically, the course of treatment is usually 3-6 months, can be repeated. It can effectively inhibit hair growth and treat acne. (2) Post-progestin semi-cycle therapy: It can regulate menstruation and protect the endometrium. It also has an inhibitory effect on excessive LH secretion and can achieve the effect of restoring ovulation. (2) Reduce high androgen levels: (1) Oral contraceptives: such as ethinyl estradiol cyproterone tablets need 6-12 months to improve hirsutism. (2) Glucocorticosteroids: For polycystic ovary syndrome where the excess androgens are of adrenal origin or mixed adrenal and ovarian origin. The commonly used drug is dexamethasone. 0.25 mg orally every night, which can effectively inhibit the concentration of dehydroepiandrosterone sulfate. The dose should not exceed 0.5mg daily to avoid excessive inhibition of pituitary-adrenal axis function. (3) Spironolactone: The anti-androgen dose is 40-200mg daily, and the treatment of hirsutism requires 6 to 9 months of medication. If irregular menstruation occurs, it can be used in combination with oral contraceptives. 3.Improve insulin resistance: Insulin sensitizers such as metformin 250-500mg 3 times a day are commonly used for obese or insulin resistant patients. Take it continuously for 2 to 3 months. 4. Ovulation induction: Clomiphene is the first-line drug for PCOS infertility, 50mg daily for 5 days starting on the 5th day of menstruation, with temperature measurement and ultrasound follicle monitoring during the dosing period. If ovulation does not occur, the dose can be increased to 100mg daily for the next cycle. For CC-resistant PCOS patients, gonadotropins and letrozole can be applied. (iii) Surgical treatment: It is suitable for patients with PCOS infertility and is the second-line method of infertility treatment for PCOS patients. 1. laparoscopic electrocautery or perforation of the ovary (LOD): it is mainly used as a second-line treatment for patients with clomiphene resistance and is more effective for those with elevated LH and free testosterone. risk. The potential problems of LOP include ineffective treatment, pelvic adhesions and low ovarian function. 2. Ovarian wedge resection: wedge resection of 1/3 of the ovaries bilaterally can reduce androgen levels, alleviate symptoms of hirsutism and improve pregnancy rates. The incidence of postoperative perivarian adhesions is high and is no longer commonly used in clinical practice. (iv) Assisted reproductive technology: IVF is the third-line treatment for PCOS infertility, mainly for PCOS patients who have ovulation but still have no pregnancy after applying standard ovulatory cycle treatment for more than 6 months, or patients who have no ovulation with multiple drug ovulatory treatment and adjuvant therapy and are urgently waiting for pregnancy, can choose the assisted reproductive technology of embryo transfer.