The treatment of immune thrombocytopenia in diabetic patients needs to be individualized according to the platelet count and the patient’s bleeding manifestations. If the platelet count is more than 30*10^9/L and there is no obvious bleeding manifestation (blood blisters in the oral mucosa, active bleeding in the nasal cavity, black stools, etc.), the patient can be left untreated for the time being, and the blood routine should be rechecked regularly and the patient should be observed to see if there is any new hemorrhagic manifestation. If the platelet count is less than 20*10^9/L, the patient should be confined to bed, avoid trauma, and be given hemostatic drugs and glucocorticosteroids such as dexamethasone, prednisone or human immunoglobulin to raise the platelet count if necessary. During the use of glucocorticosteroids need to test blood glucose, because glucocorticosteroids will make blood glucose rise significantly, should strengthen the treatment of hypoglycemia, to avoid the occurrence of diabetic ketoacidosis. It is recommended that the patient should consult the hematology department in a timely manner, and individualized treatment plan should be formulated by the specialist after assessing the condition, and the routine blood test should be repeated regularly to dynamically monitor the change of platelet count, and to actively prevent the occurrence of intracranial hemorrhage, gastrointestinal hemorrhage, and other serious bleeding complications.