High neutrophil percentage

High neutrophil percentage is usually seen as a result of physiological factors, but may also be due to bacterial infections, hemorrhage, tissue cell necrosis, and malignancy. Neutrophil percentage is the proportion of neutrophils in the number of white blood cells, so an increase in neutrophils or a decrease in other white blood cells can cause a high neutrophil percentage. The percentage of neutrophils is physiologically high during meals and emotional stress, strenuous exercise, high temperatures and cold environments. In addition, in the afternoon will be higher than in the morning, female pregnancy will also appear neutrophil percentage elevation, these are normal physiological phenomena, the magnitude of the elevation is not large, generally can recover to normal values, no special treatment. Second, pathological high: 1, bacterial infection: bacterial infection can lead to a significant increase in neutrophils, so that the percentage of neutrophils is high. The common ones include respiratory infections, intestinal infections, urinary tract infections, mastitis, appendicitis, cholecystitis, etc. caused by various bacteria. Infections require the application of antibiotics, such as cefaclor, ofloxacin, etc. If necessary, the infected lesions need to be removed, and in severe cases, drainage of exudate is also required; 2. Hemorrhage: severe trauma resulting in massive bleeding, gastrointestinal hemorrhage, hemorrhage during pregnancy, etc. The body produces a stress response to hemorrhage, resulting in increased secretion of adrenocorticotropic hormone. This promotes the release of neutrophils from the bone marrow reserve pool into the circulation, resulting in an increase in the percentage of neutrophils. The situation of hemorrhage is very critical and can be life-threatening in serious cases, so immediate rehydration, blood transfusion and hemostatic treatment should be carried out. 3. Tissue cell necrosis: High neutrophil percentage can also occur in the event of severe trauma, burns, intestinal obstruction, pulmonary infarction, myocardial infarction, etc. resulting in tissue cell necrosis. It may be related to increased proteolytic products and hypoxia promoting increased release of bone marrow reserve pool. Should actively treat the original disease, lift the cause of necrosis, in order to restore the percentage of neutrophils to normal; 4, malignant tumors: leukemia and various tumors in the late stage, some tumors can produce granulopoietin, can appear high percentage of neutrophils. In addition, late stage tumor necrosis breakdown products can attract the bone marrow reserve pool to release neutrophils, generally according to the specific cause of radiotherapy; 5, rheumatic immune diseases: adult Still’s disease, vasculitis, dermatomyositis, etc. are often manifested as neutrophil elevation, resulting in a high percentage. These diseases mainly need to be treated for the immune system, mainly drug therapy, commonly used drugs including non-steroidal anti-inflammatory drugs, glucocorticoids, etc., so as to improve clinical symptoms; 6, long-term application of glucocorticoids: long-term application of glucocorticoids can stimulate the hematopoietic function of the bone marrow, so that neutrophil production increased. It is necessary to follow medical advice to suspend the medication, adjust the treatment plan, and observe the change of neutrophils.