Cirrhosis is generally not a primary cause, but the end result of multiple causes. The prognosis of cirrhosis is related to the etiology, degree of liver function compensation and complications, and cannot be generalized. Factors affecting the prognosis of cirrhosis include the following: causes of cirrhosis: alcoholic cirrhosis, biliary cirrhosis, liver stasis, etc. If the causes can be eliminated before the cirrhosis progresses to the decompensated stage, the lesions may tend to be quiescent or even reversible. However, for cirrhosis caused by viral hepatitis, the prognosis is often poor due to the difficulty of completely removing the curative factors, and we can only try to delay the progression. Staging of cirrhosis: There is a clinical grading standard for the compensatory capacity of the liver, called Child-Pugh grading, which is closely related to the prognosis, with grade A being the best and grade C the worst. Simply put, the better the compensatory capacity, the earlier the staging, the better the prognosis and life expectancy, and vice versa. Complications of cirrhosis: Complications are the ultimate cause of death in patients with cirrhosis. Complications such as hepatic encephalopathy, hepatorenal syndrome, ruptured esophagogastric varices and bleeding may directly lead to death, and are also contraindications to treatment modalities such as liver transplantation, which are very detrimental to patients’ prognosis. Overall, the prognosis of patients without complications is generally better than that of patients with complications. Therefore, some types of cirrhosis can be cured and others can delay progression as much as possible, while some advanced cirrhosis with poor compensatory capacity and severe complications often have a poor prognosis.