Tooth root exfoliation sensitivity is a complication of periodontitis, mainly due to the resorption of the alveolar bone, which leads to root exfoliation. There are dentin tubules in the roots, and if the pressure changes, the nerve will be irritated. After the root is exposed, the root can be treated by desensitization. Desensitization is divided into drug desensitization, laser desensitization, or a combination of both together, and can be done at the dentistry department. Sensitization of root exfoliation can also be done by applying bonding agents to isolate the irritation, which can take effect in about 3 months. Patients can also purchase their own anti-allergy toothpaste from the supermarket, which can provide a better anti-allergy effect. Tooth root leakage is inseparable from periodontitis and requires timely periodontal treatment to avoid further exposure of the tooth root leading to increased sensitivity.