Recently, the Eastern Spine Surgery Department performed a minimally invasive surgery for a patient with a cervical fracture dislocation with a single joint strangulation. The successful implementation of this surgery was a perfect combination of minimally invasive concept, minimally invasive technique, minimally invasive equipment and minimally invasive effect, reflecting the fact that our department has reached a higher level in minimally invasive spine technology. The patient was a middle-aged male with neck pain, limited mobility and pain and numbness in both upper extremities after a car accident, and a history of previous craniocerebral trauma surgery. After admission, he was diagnosed with a cervical 5/6 fracture dislocation with left-sided articular syndesmosis and compression of the cervical medulla in the corresponding segment. The main disadvantage is that it destroys the posterior muscle-ligament complex; then the anterior cervical bone graft fusion is performed, which takes 1.5 hours, and each operation requires 2-3 physicians are involved in the surgery. Since 2009, the Department of Spine Surgery has carried out a lot of work in minimally invasive access technology, mainly in lumbar spine surgery. 60% of treated lumbar spine surgeries use this technology, covering lumbar disc herniation, lumbar spinal stenosis, lumbar spine slippage, etc., involving single or multiple segments with minimal postoperative trauma, and it has been a question of exploration whether the same can be used in cervical spine surgery. To address the characteristics of this patient’s case and the mechanism of injury, the whole department decided to perform a combined posterior-anterior cervical spine surgery under minimally invasive access, in which a Quadrant channel was placed in the muscle space on the posterior side of the cervical spine to directly reveal the strangulated synovial joint, and a high-speed grinding drill was used to remove the dislocated part of the synovial joint. The surgery was performed in 45 minutes with 10 ml of bleeding and only one assistant. The patient recovered quickly after surgery due to the greatly reduced operative time, minimal bleeding, and less damage to the muscle ligaments. Spine surgery has now gradually entered the era of minimally invasive surgery and precision surgery. Small incision techniques, percutaneous techniques, access techniques, endoscopic techniques, and microscopic techniques constitute the main part of minimally invasive spine surgery nowadays, complementing traditional open surgery and serving patients in all aspects.