The prognosis of patients with pulmonary fibrosis is closely related to their condition, individual differences and the way they are cared for later in life, and cannot be generalized. The prognosis of patients with pulmonary fibrosis is mainly related to their own condition. If pulmonary fibrosis is mild and is treated promptly, patients can survive for a long time. However, the majority of pulmonary fibrosis symptoms are chronic, and the older the age of onset, the longer the duration of the disease. If the disease is detected in time and treated in a hospital as soon as possible, patients with pulmonary fibrosis who have mild symptoms, are in good health, and have a slow progression of the disease can live for up to one or two decades, or even more. The acute form of the disease is less common, and its typical clinical manifestations are physical weakness, night sweats, emaciation, and occasional sputum and blood. The key point of management is to avoid exacerbation of the disease and loss of original respiratory function. How long one can live depends on the extent and progression of the lesion. Most patients die from respiratory and circulatory failure, which eventually leads to respiratory failure. Patients with end-stage pulmonary fibrosis should consider lung transplantation. In general, it is important to develop good habits and to have regular lung function checks so that pulmonary fibrosis can be detected early and prevented effectively.