As we all know, patients with rheumatoid arthritis (RA) have swollen and painful joints, and the disease persists, even with joint deformities, causing great pain to patients’ life and work. Once patients know that they have RA, their first reaction is fear, and their greatest wish is to find a cure. As doctors, we do not want to have a cure, but we must tell you the cruel fact that less than 10% of patients have the disease in a transient manner, and after treatment, the disease can be completely remitted or in long-term remission, and the treatment is terminated. When you know this fact you may feel desperate for treatment and go looking for a partial room or a panacea for the root cause, we advise you not to do this, the people of the earth still have found a cure for this disease, a partial room or a panacea for the root cause will only make you lose the best time for treatment and push yourself to the end. At present, human beings can not do the root cause of many diseases, such as diabetes, hypertension. So what to do? Live with the disease, a very rational thinking. Modern medicine cannot cure RA, but with standardized treatment, clinical remission is entirely possible. Why can’t it be cured? The so-called cure is to remove the cause and cure the disease, and the cause of RA is not known, let alone removed. Current research suggests that RA develops on the basis of a susceptibility gene, with external factors acting as triggers, leading to the destruction of immune tolerance and the production of autoantibodies to destroy one’s own tissues. Current treatments are aimed at maintaining immune tolerance, suppressing autoantibody production and inflammation, and bringing the disease under control to achieve clinical remission. What does clinical remission mean? The American College of Rheumatology has proposed the following criteria for clinical remission of RA: 1. morning stiffness of no more than 15 minutes; 2. no fatigue; 3. no joint swelling and pain; 4. no joint tenderness; 5. no swelling of joints or soft tissues; 6. blood sedimentation of less than 20 mm/hour in men and less than 30 mm/hour in women. If five or more of the above six items are met, clinical remission is defined. The key to achieve clinical remission lies in early diagnosis, early and correct treatment, and adherence to long-term treatment.