Etiology and clinical manifestations of cutaneous lipoma

Causes of cutaneous lipoma From the pathogenesis and combined with modern biomolecular theory, we finally concluded that the root cause of various types of lipoma formation is “lipoma tumorigenic factor”. However, under the influence of various internal and external environmental factors, the activity of this lipoma-causing factor is active and has certain activity. When the body’s resistance decreases, the immune cells such as lymphocytes and mononuclear phagocytes in the body have a reduced ability to monitor the tumor-causing factor, coupled with changes in the internal environment, the stimulation of chronic inflammation and abnormal fat metabolism in the body, the activity of lipoma-causing factor is further increased. The activity of lipogenic factors is further enhanced to combine with certain gene fragments in normal cells of the body, forming abnormal gene mutations and causing normal adipose fine lipoma. The abnormal proliferation of cells and surrounding tissue cells leads to the deposition of adipose tissue and the protrusion of lumps to the body surface or various internal organs, which is called lipoma. 1.Dietary factors Excessive alcohol consumption, frequent consumption of fatty meat, animal offal, fish without scales or egg yolk, etc. Because of excessive consumption of fatty and greasy products and high cholesterol food, it can cause dampness and heat in the spleen and stomach, phlegm and dampness, and dysregulation of transportation and transformation, i.e. excessive newborn adipose tissue, so that too many fat cells in the body are heterogeneous and hardened. The treatment principle is: to remove heat and dampness, to strengthen the spleen and stomach, and to soften and disperse the knots. 2, the stress factor work too much pressure, irritable mood, often angry people. Because of the stagnation of liver qi, qi and blood are not smooth, the meridians are not blocked, which can cause the normal adipose tissue and stagnant blood to intertwine together, and connective tissue can be formed for a long time to wrap the fat cells, forming lipoma. Treatment principle: dredge liver and qi, invigorate blood circulation and remove blood stasis, soften hardness and disperse knots. Through the treatment to open up the meridians, dredge the blood and dissipate the fatty tumor. 3.Bad habits People who often stay up late and think too much about problems. Because of the injury to the spleen and stomach, the spleen is not healthy and the yin and yang are out of balance, so that the body’s ability to decompose fat decreases, and the original fat tissue and new fat cannot be arranged normally, forming abnormal fat tissue, i.e. “lipoma”. Clinical manifestations of cutaneous lipoma Lipoma has a thin fibrous inner membrane with many fibrous cords inside, forming many intervals longitudinally and horizontally, most commonly found in subcutaneous tissues of neck, shoulder, back, buttocks, breast and limbs, face, scalp, scrotum and labia, followed by retroperitoneum and gastrointestinal wall, etc. Very few of them can appear in the parts where there is no fatty tissue. If the proportion of fibrous tissue in the tumor is high, it is called fibrolipoma. The size of lipoma varies, most of them are flat and round or lobed with clear demarcation; those with unclear demarcation should be aware of the possibility of malignant lipoma. The tumor is soft and elastic (distinguish it from larger cysts), and some of them may have pseudo-volatility. The tumor does not adhere to the epidermis, the skin surface is completely normal, and the base is more extensive. When examining the tumor, if you press the base of the tumor with your hand, you can see the lobulated form. The skin may appear as “orange peel”. The tumor develops very slowly, and most of them have no serious adverse effects on the body, and malignant changes are rare. In addition, there is another type of multiple round or oval nodular lipomas, which are commonly found in the extremities, waist and abdomen under the skin. The size and number of these tumors are variable, and they are slightly harder than normal lipomas and painful when pressed, thus they are called painful fibrolipomas. 1.Lipoma or multiple lipomas Lipomas usually have no pain and other discomfort. The growth of lipoma is slow, and multiple lipomas are usually small and soft, and may have a pseudocystic feeling. Lipomas often occur in multiple sites and have a family history. They can be left untreated if there are no obvious symptoms. Surgical removal is only necessary if there is local pain and discomfort, if the tumor is large and affects the aesthetic appearance or if the tumor affects the function of the limbs, if the tumor grows faster and larger and malignancy is suspected, or if a solitary lipoma grows in a deeper area. Lipoma is not liposarcoma, but liposarcoma is a kind of tumor with higher malignant degree, which grows rapidly, has larger tumor and harder texture, and is mostly solitary. 2.Lipoma of neck Lipoma occurring in the neck can be solitary, multiple or diffuse growth. Generally, they grow slowly and have no conscious symptoms, but are often found unintentionally or during physical examination. Diffuse lipoma may compress the nerve and cause nerve compression symptoms, or cause limitation of neck movement, or even affect breathing and swallowing function. Examination of cutaneous lipoma 1.General ultrasound Ultrasound can determine its location, size, texture, and whether it is substantial or cystic. 2.Color ultrasound and angiography Color ultrasound, can directly see the blood supply of the mass, if the blood supply is rich, consider the possibility of malignant tumor. Color ultrasound or angiography can clearly determine its boundary, whether the envelope is intact, and the relationship between surrounding large blood vessels and important tissues such as nerves. 3.Blood examination ah can understand liver function, glucose and lipid metabolism, etc. Diagnosis of cutaneous lipoma Diagnosis of this disease is mainly based on symptoms and physical examination, especially the physical characteristics of the mass. Treatment of cutaneous lipoma The only effective treatment is surgical excision. Smaller (within 1 cm in diameter), multiple lipomas can be temporarily observed without treatment after diagnosis. In larger cases, surgical excision is recommended.