Patient: In May 2007, a physical examination revealed a heart rate of over 120 beats per minute, and the doctor recommended laboratory tests for FT3, FT4 and TSH to determine hyperthyroidism. In September 2007, anti-thyroglobulin antibody test: 869.5 (reference value: 0-115 IU/MI) Thyroid peroxidase antibody: 206.8 (reference value: 0-34 IU/MI) Hashimoto hyperthyroidism was confirmed. Recent treatment status is as follows October 8, 2008 Cebu hospital laboratory results are as follows: FT3: 5.04 (reference value: 3.67-10.43 pmoI/L) FT4: 15.32 (reference value: 11.2-20.1 pmoI/L) TSH: 1.35 (reference value: 0.20-7.00 MIU/L) Doctor recommended medication maintenance: Sage (2.5mg per day, 25ug per day of Eugenol) The hospital laboratory results on October 9, 2008 were as follows Thyroglobulin antibody: 36.6 (reference value: 0-30%) Thyroid microsomal antibody: 31.3 (reference value: 0-20% I) The doctor recommended the maintenance of the medication: 2.5mg per day of Sage, 25ug per day of Eugenol The hospital laboratory results on November 4, 2008 were as follows FT3: 5.21 (reference value: 3.67-10.43 pmoI/L) FT4: 18.4 (reference value: 11.2-20.1 pmoI/L) TSH: 1.31 (reference value: 0.20-7.00 MIU/L) Doctor’s recommendation: Sage 2.5mg/day, Eugenol 25ug/day Hospital test results on January 9, 2009 FT3: 5.34 (reference value: 3.67-10.43 pmoI/L) FT4: 18.66 (reference value: 11.2-20.1 pmoI/L) TSH: 1.91 (reference value: 0.20-7.00 MIU/L) The doctor suggested that the dosage should be maintained: 2.5mg of Sage for two days and 25ug of Eugenol for two days from Jan. 15 to Feb. 16. From February 16 to March 16, Sage 2.5mg for three days and Eugenol 25ug for two days. The results of hospital tests on March 11, 2009 are as follows: FT3: 4.5 (reference value: 3.67-10.43 pmoI/L) FT4: 12.84 (reference value: 11.2-20.1 pmoI/L) TSH: 1.5 (reference value: 0.20-7.00) (MIU/L) Doctor’s recommended medication maintenance: 2.5mg for four days of Sage from March 16 to April 28, and 25ug for four days of Eugenol from April 28 to May 2, 2.5mg for seven days of Sage, and 25ug for seven days of Eugenol April 30, 2009 hospital laboratory results are as follows: FT3: 4.39 (reference value: 3.67-10.43 pmoI/L) FT4. 14.29 (reference value: 11.2-20.1 pmoI/L) TSH: 1.02 (reference value: 0.20-7.00 MIU/L) Anti-thyroglobulin antibody TG-Ab: 964.1 (reference value: 0-115.0 KIU/L) Thyroid peroxidase antibody TPO-Ab: >600 (reference value: 0-34 KIU/L) From FT3, FT4, and TSH test results have been normal since February 2008, and it has been more than a year since the treatment of hyperthyroidism. If FT3, FT4 and TSH are still normal, can I have a baby if I stop taking the medication for two months? But the thyroid antibodies are very high. Now I want to consult my doctor if I can consider taking the medication to get pregnant, if so, can I switch from Sage to Propylthiouracil now and take FT3, FT4 and TSH to keep it normal to have a baby? Doctor: It is best not to get pregnant during hyperthyroidism treatment. According to the situation you have provided, you have been treated for 2 years and your nail function has been controlled normally, so you can consider stopping the medication. Check the thyroid function in 1 month, 2 months, 3 months and 6 months after stopping the medication, if it is normal, you can consider pregnancy. It should be noted that pregnant women with elevated levels of thyroid autoantibodies (anti-thyroglobulin antibody TG-Ab, thyroid peroxidase antibody TPO-Ab) are prone to abnormal thyroid function in the postpartum period. Patient: Some doctors say that high autoantibodies to the thyroid gland can easily recur. I am worried that a recurrence of hyperthyroidism during pregnancy will affect the fetus. Doctor: There is no medication that can lower the level of thyroid autoantibodies (TGA, TPO-Ab). It is still necessary to check your thyroid function regularly during pregnancy.