Interstitial pneumonia in the elderly is generally not serious. Interstitial pneumonia is divided into ground glass-like changes and cellular changes. Ground glass-like changes are generally caused by bacteria, viruses, atypical pathogenic bacteria, and fungi, while cellular changes generally have an unclear etiology and no effective clinical treatment measures. The prognosis is better for glassy changes, while cellular changes are complicated and have a poor prognosis. When a patient presents with interstitial changes, routine blood tests, C-reactive protein, calcitoninogen, mycoplasma antibodies, as well as sputum culture, viral antibodies and other relevant tests are needed to evaluate the possible infecting pathogen and to take appropriate anti-infective, anti-viral, as well as anti-Atypical pathogenic and anti-fungal treatments according to the pathogen. If the patient has interstitial changes in the form of honeycomb, small doses of erythromycin, fullux, and glucocorticoids may be tried.