Vitiligo is a common clinical skin disease and its diagnosis is easier in most cases, but in a few cases (especially in early stages), its manifestations may be similar to many other skin diseases, making diagnosis and treatment difficult. The following are some of the skin diseases that need to be clinically distinguished from vitiligo.
I. Genetic skin diseases
①Albinism
②Pigmentation disease
③Nodular sclerosis
④Vogt-Koyanagi syndrome
⑤Waardenburg syndrome
⑥Chediak-Higashi syndrome
⑦Hermansky-Pudlak syndrome
⑧Hereditary pancytopenia
⑨Hereditary symmetrical limb pigmentation anomaly
⑩Depigmented pigment incontinence (nevus-like hypopigmentation)
Infectious skin diseases
①Black fever
②Leprosy
③ Onchocerciasis
④Pinta
⑤Phase II syphilis
⑥Schistosomiasis
⑦Yaws disease
III. Neoplastic dermatoses
①melanoma + depigmentation.
② Hypopigmented mycosis fungoides
IV. Exogenous factors
①Arsenic keratosis
②Dermabrasion
③Liquid nitrogen freezing
④Vitaminic acid
⑤Azelic acid
⑥hydroquinone monobenzyl ether
⑦Corticosteroid local seal
V. Nutritional deficiency
①Selenium deficiency
② malignant malnutrition
Sixth, physical and chemical factors
①Burn injury
②Radiation
③Phenols/catechols (Chemical leukoderma)
VII. Inflammatory skin diseases
①Atopic dermatitis
②Discoid lupus erythematosus
③Psoriasis
④Chronic mossy furunculosis
Eight, other skin diseases
①Sclerosing atrophic moss
②Scleroderma
③Anemic nevus
④White pityriasis
④Depigmented nevus
⑤Unilateral nevus-like capillary dilatation
⑥Idiopathic punctate hypopigmentation
⑦Progressive macular hypopigmentation