Herpetic dermatosis, is a kind of autoimmune skin disease that is prevalent in middle-aged and elderly people. Due to the disorder of the body’s autoimmune system, the patient’s body produces antibodies against their own skin (that is, their own people fight with their own people), and then blisters appear on the skin blisters, accompanied by vesicles, oozing, infection, pain or itching. Many of these patients will develop ulcerated vesicles on the oral mucosa and have difficulty eating, which seriously affects the patient’s quality of life. Some patients in the early stage of eczema-like changes, the trunk and limbs appear red papules and wind, blisters, accompanied by obvious itching, blood routine eosinophils increased significantly, according to the ordinary eczema treatment, the application of anti-allergic drugs and topical ointment are ineffective. For patients with long lasting eczema, it is recommended to go to the hospital for histopathology and immunofluorescence and other related examinations, except for herpetic dermatosis.