Some patients with early stage breast cancer often have local discomfort, especially postmenopausal women, who sometimes feel mild pain and discomfort in one breast, or sinking, soreness and discomfort in the back of one shoulder, even involving the upper arm on that side. A lump the size of a pea can be palpated in the breast, hard and movable, usually without obvious pain, but a few have paroxysmal vague pain, dull pain or stabbing pain. Changes in the appearance of the breast can be seen in the form of skin elevation at the lump, some local skin orange peel, or even edema, discoloration, eczema-like changes, etc. There is overflow from the nipple. If the overflow is bloody or plasma blood, special attention should be paid for further examination. Regional lymph node enlargement, with ipsilateral axillary lymph node enlargement being the most common; supraclavicular lymph node enlargement is already in advanced stage. Patients who are pre-menopausal or perimenopausal at the time of onset of disease should not only firmly grasp the critical period of treatment 5 years after surgery, but also need to reasonably “replace” the program according to the different physiological characteristics before and after menopause, and maintain close contact with the attending physician, so as to minimize metastasis and recurrence, improve the quality of life and prolong life.