Stomach tumor will usually shrink through chemotherapy for patients with advanced stomach cancer. Stomach cancer in advanced stage is not suitable for surgery, and is usually treated by chemotherapy and immunotherapy etc. Chemotherapy is an effective measure for treating stomach cancer, and those who can not have surgery should consider chemotherapy. Stomach tumors should be shrunk by chemotherapy, but it may also produce adverse reactions of chemotherapy, such as hair loss, vomiting, nausea, dizziness, drop of blood cells and other adverse reactions. Patients with advanced gastric cancer should take chemotherapy under the guidance of physician’s interview and pay attention to the adverse reactions and precautions as well as contraindications of chemotherapy. People who are allergic to chemotherapy drugs should not force chemotherapy, and if the side effects of chemotherapy are serious, chemotherapy should not be continued. During chemotherapy for advanced stage of stomach cancer, if the patient is not feeling well, he/she should actively reflect to the attending physician and handle the situation according to the standard.