Cryotherapy wart after the blistering, is caused by low temperature leads to local vascular stagnation, swelling, is a normal phenomenon. The size of the bubble can be treated under the guidance of a professional doctor: 1, the bubble volume is small and no pain: can be self-healing, then no special treatment. The main thing is to keep it dry and avoid getting wet, and you can prevent infection with external rubbing of vital iodine. Usually after 3-5 days, the blisters can be self-absorption, dry, crust, fall off; 2, bubble <1cm and accompanied by pain: If the patient in the liquid nitrogen cryotherapy warts, the volume of the bubble <1cm, and accompanied by obvious swelling and pain, then you need to go to the hospital. In the doctor's guidance to use iodine volts to apply the wounded area, and then a sterile syringe to poke the wall of the bubble, the bubble liquid to deal with clean, appropriate bandage to play a role in pressure, after 2-3 days can also gradually heal; 3, bubble > 1cm: patients are recommended to hospital treatment. By professional doctors using medical scissors to cut through the vesicle wall, the erosion surface with antiseptic and antibacterial solution wet dressing, such as potassium permanganate solution, boric acid solution, and benzalkonium chloride solution, etc.. To avoid secondary infection, topical application of Bactrim cream, fusidic acid cream, erythromycin ointment, etc., together with gauze wrapping of the affected area. During the treatment period, patients are advised to keep the trauma area dry. Also do not eat spicy food such as chili, leek, mustard, ginger, etc. Avoid doing strenuous exercise to avoid producing sweat to stimulate the wound.