Esophageal cancer is a common malignant tumor of upper gastrointestinal tract in China, with the age of onset mostly above 40 years old and the main symptom is progressive dysphagia. At present, the treatment methods of esophageal cancer usually include surgery and radiotherapy. In recent years, with the development of minimally invasive surgery technology, thoracoscopic and laparoscopic technologies have been gradually popularized, and combined thoracolaparoscopic esophageal cancer surgery has gradually become the direction of minimally invasive esophageal surgery, which can be performed through a few small holes in the chest and abdomen. In this method, three to four small 1 cm holes are made in the chest and abdomen, and lumpectomy instruments are inserted to free the esophagus and stomach, remove the lymph nodes and reconstruct the digestive tract. Compared with conventional open-heart surgery, the advantages of this technique are less impact on the chest and abdominal organs, less surgical trauma, significant reduction of postoperative pain, strong coughing, rapid postoperative recovery, and the ability to get out of bed early, which greatly reduces postoperative pulmonary complications. Since the anatomy of esophageal cancer surgery is complex and involves several anatomical regions such as neck, chest and abdomen, combined thoracoscopic and laparoscopic surgery is more difficult. This is because esophageal cancer surgery involves not only the removal of esophageal tumor and lymph nodes in the chest, but also the freeing of the stomach in the abdomen and the reconstruction of the digestive tract. At present, we have successfully performed combined thoracoscopic and laparoscopic radical esophageal cancer surgery for hundreds of esophageal cancer patients, and all of them have been discharged successfully. Combined thoracoscopic and laparoscopic radical esophageal cancer surgery adopts thoracoscopic resection of esophageal tumor, combined with laparoscopic freeing of stomach, and at the same time can completely clear the lymph nodes in the chest and abdomen, achieving the same effect of radical tumor treatment as that of open chest surgery. Since there is no open incision in the chest and abdomen, the muscle movement of chest and abdomen is not affected during breathing, which is more conducive to the recovery of respiratory function after surgery. Radical surgery for esophageal cancer under total lumpectomy can reduce the trauma caused by surgery and many postoperative complications caused by it, and provides patients with esophageal cancer with the opportunity of minimally invasive surgery for radical treatment.