Kidney disease stage III usually refers to chronic kidney disease stage III. Kidney disease is mainly staged according to glomerular filtration rate, which is correlated with creatinine concentration. If the creatinine value is 115 μmol/L, it mostly indicates a decrease in glomerular filtration rate and impaired renal function, and chronic kidney disease needs to be considered, with stages II-III possible; if the glomerular filtration rate is <30-60 ml/min at the same time, it is chronic kidney disease stage III. In clinical practice, chronic kidney disease is also usually divided into stage IIIa and stage IIIb. In stage IIIa, the glomerular filtration rate is mildly to severely reduced, ranging from 45-59 ml/min; in stage IIIb, the glomerular filtration rate is moderately to severely reduced, ranging from 30-44 ml/min. The presence of chronic kidney disease may be due to a variety of causes, such as glomerular insufficiency, diabetic nephropathy, renal arteriosclerosis, hypertension, renal vascular disease, hereditary nephropathy, etc. At this time, patients may experience edema, nausea, vomiting, weakness, loss of appetite, and even renal anemia. Patients are advised to consult their doctors and have other tests done in a timely manner so that they can be treated with medication, surgery or dialysis according to their specific condition and tolerance level. Early treatment can help improve symptoms, protect kidney function and prevent further deterioration of the condition.