Immediately after a bleeding rat bite, it is recommended to use water blended with soap or other weak alkaline detergent and certain pressure of water to wash alternately and repeatedly, then clean the wound and the area around the wound with saline or purified water, and then clean the residual liquid at the wound with sterile gauze or a clean towel to avoid residual bruises or soapy water, etc. in the wound. If iodophor solution or 75% disinfectant alcohol is available, it can be applied to the wound for disinfection treatment. After simple treatment, it is recommended that the wound be taken to a hospital immediately for further treatment and that the need for rabies vaccination or renal syndrome hemorrhagic fever vaccination, etc., be determined based on the condition. If the wound is deep, the need for tetanus vaccination should also be considered. If the patient’s bite wound is septic, further treatment such as disinfection, debridement, and dressing is usually required. If the patient has fever, swollen lymph nodes, rash, redness and swelling on the skin surface, it may be an allergic reaction to substances in the saliva of the rat or a secondary bacterial infection, and prompt anti-allergic treatment or antibacterial treatment, such as the use of loratadine, cetirizine, cefuroxime and other drugs, is recommended. If a patient has symptoms of respiratory distress, rapid heartbeat or even shock after being bitten by a rat, he or she should be sent to a hospital immediately for anti-shock treatment.