All antihypertensive drugs have certain side effects. Patients are advised to choose the right drug for themselves according to their symptoms and doctor’s diagnosis. Currently, diuretics, calcium channel blockers, beta-adrenergic receptor blockers, angiotensin-converting enzyme inhibitors, and angiotensin II receptor blockers are commonly used in clinical practice to lower blood pressure. 1. diuretics: such as furosemide and hydrochlorothiazide, may affect patients’ blood glucose, blood lipids, and blood uric acid metabolism after use. In general, it is not recommended for patients with renal dysfunction. 2. calcium channel blockers: such as nifedipine and lacidipine, may cause palpitations, flushing, edema and other symptoms when taken, and should be used with caution in patients with heart failure, heart block and abnormal liver and kidney function. 3. beta-adrenergic receptor blockers: such as propranolol hydrochloride, labetalol, etc., may cause patients to experience heart rate Slowing down and other symptoms. This drug has less effect on the kidney and can be used in patients with renal insufficiency, but patients with acute heart failure need to be used with caution; 4, angiotensin-converting enzyme inhibitors: such as captopril, enalapril, etc., may cause patients to develop a dry cough, angioneurotic edema and other adverse reactions, it is recommended that patients with hyperkalemia, renal insufficiency and other diseases be used with caution; 5, angiotensin II receptor blockers: such as irbesartan, coxsartan, valsartan, etc., hepatic and renal receptor blockers. Valsartan, etc., need to be used with caution in patients with liver and kidney dysfunction.