Membranous ventricular septal defect tumors are more common and interventional treatment is the routine treatment. If one occluder cannot be completely occluded, two occluders can be considered. Our department has successfully applied double blockers to treat many similar patients. A typical case is attached. The child, male, 6 years old, was admitted to the hospital with “heart murmur found since childhood for more than 5 years”. He was diagnosed with “congenital heart disease and ventricular septal defect (membranous tumor)” based on his medical history, physical signs, and ancillary examinations (ECG, chest X-ray, and echocardiogram). After thorough preparation, interventional closure of the ventricular septal defect was performed under general anesthesia. The operation was successful and he was discharged with a 5-day hospital stay. After the operation, the patient was reviewed several times with good results. The main procedure is shown in Figure 1, Figure 2, Figure 3, Figure 4 and Figure 5. The patient’s parents strongly requested for interventional blocking treatment instead of traditional open-heart surgical repair; 2. Figure 1 Left ventriculogram, showing the membranous tumor of the ventricular septal defect, with two breaches on the right ventricular surface at a distance Figure 2 Application of the blocker to block the upper opening and imaging, showing another opening Figure 3 Establishment of the second track through the ventricular defect Figure 4 Left ventriculogram after application of two blockers, with no residual shunt Figure 5 Release of two blockers, with satisfactory morphology