Ventricular septal defect (ventricular defect for short) is a relatively common congenital heart disease in clinical practice, and its incidence accounts for about 20%. It is usually divided into four types: perimembranous, intracrural, subcrural and muscular defects, among which perimembranous ventricular defect is the most common, accounting for about 75%. In the past, surgical open-heart surgery was the only treatment method, but in recent years, with the rapid development of cardiovascular interventional techniques and equipment development, interventional methods have gradually become the preferred treatment for ventricular defects. At present, nearly 10,000 cases of ventricular defect interventions have been carried out in China, and the success rate can be as high as 95% or more, far more than foreign countries, providing a large number of cases and experiences for the world. Because of the complex and diverse location, shape, size and relationship with surrounding tissues and structures of ventricular defects, how to select suitable cases for interventional treatment is to ensure successful perfusion. Based on the experience of interventional treatment of ventricular defects in a large sample in China and combined with relevant literature reports, we believe that the indications and contraindications for interventional treatment of membranous ventricular defects are: Indications 1. age > 3 years, weight ≥ 8 kg, with increased left ventricular volume load A history of enlarged heart, recurrent heart failure, infective endocarditis; mild to moderate pulmonary hypertension without right-to-left shunt; 2, left ventricular surface defect of 3-10 mm, the diameter of the defect should be ≤8 mm in children; the distance of the defect edge from the aortic right coronary valve is ≥1 mm and from the tricuspid valve is ≥2 mm, without obvious tricuspid valve developmental abnormalities and moderate tricuspid regurgitation or above. In the presence of aortic right coronary valve prolapse, but the valve leaflet does not obscure the defect orifice and is not combined with aortic regurgitation; 3, with ventricular septal membrane aneurysm, the diameter of the left ventricular surface of the defect should be ≤ 20 mm, the right ventricular surface has a small exit and is firmly adhered; when the right ventricular surface is porous, the diameter of one of the defect holes should be ≥ 2 mm; the aneurysm formed by the membrane aneurysm cannot cause stenosis of the right ventricular outflow tract; 4, after surgical repair of the membrane ventricular defect, there are hemodynamic The residual shunt of the change; 5, combined with interventional indications of atrial septal defect, arterial catheterization, pulmonary valve stenosis and myocardial ventricular defect, etc., can be simultaneously interventional; 6, ventricular septal perforation after myocardial infarction or post-traumatic ventricular defect. Contraindications 1.Ventricular defect has a tendency to close naturally; 2.Severe combined pulmonary hypertension resulting in right-to-left shunt; 3.Membrane ventricular defect local anatomy is not suitable for interventional treatment or the defect is too large; 4.Combined with other congenital heart malformations must be corrected by open-heart surgery.