One of the typical symptoms of acute pancreatitis is epigastric pain, and pain in acute pancreatitis can be relieved by medication, with body position and life care. 1. Drugs for pain relief: When acute pancreatitis brings upper abdominal pain, you can apply pantoprazole, growth inhibitors and other drugs to achieve the purpose of pain relief. When the pain is particularly severe, you can also apply pethidine for pain relief. The use of drugs need to be guided by a doctor. 2. with the position: acute pancreatitis patients with pain, you can take the bend over the knee position, the position has a certain role in reducing pain. 3. Nursing care: the pain of acute pancreatitis patients will increase after eating, should be fasting for a period of time, and maintain the patient’s water, electrolyte balance. It is recommended that when symptoms of acute pancreatitis occur, you should go to a regular hospital in time.