Patient: My foot was burned by hot water last night, no blisters at that time, but this morning I got up and found blisters, about 2 cm, I don’t know what to do. It is a simple compress with toothpaste and soy sauce, and I want to know what medicine to use or how to deal with it better? Doctor: burns 48 hours plasma oozing, at any time its bubble. Small bubble, can be absorbed by itself; large bubble (more than 1 cm in diameter), must be under strict sterile disinfection, low drainage (pick through), to prevent infection. Because of the professional nature of burns, it is recommended to seek medical attention at a regular hospital burn specialty.