Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease with multisystem damage and multiple autoantibodies represented by antinuclear antibodies in the serum. The course of the disease is characterized by alternating remission and acute exacerbations, and the prognosis is poor for those with visceral (renal and central nervous) damage. The prevalence of this disease in China is O.7-1/1,000, higher than the 1/2,000 reported in Western countries, and is more common in women, especially those of childbearing age between 20 and 40. Through early diagnosis and comprehensive treatment, the prognosis of this disease is significantly improved. Most patients with active SLE have systemic symptoms. About 90% of patients have fever of various fever types during the course of the disease, especially low and moderate fever, which should exclude infectious factors. 1) Skin and mucous membranes: butterfly erythema, discoid lesions, photosensitivity, erythema or papules, oral, vulvar or nasal ulcers, hair loss, etc.; 2) Joints and muscles: arthralgia, arthralgias, myalgia, muscle weakness, ischemic osteonecrosis, etc.; 3) Blood system: leukopenia, anemia, thrombocytopenia, lymph node enlargement, splenomegaly, etc.; 4) Nervous system: headache, peripheral neuropathy, epilepsy, etc. 5) Cardiovascular system: pericarditis, myocarditis, endocarditis, etc.; 6) Vascular lesions: Raynaud’s phenomenon, reticulocytosis, arterial and venous embolism, recurrent miscarriage, etc.; 7) Pleura and lung: pleurisy, interstitial lung fibrosis, lupus pneumonia, pulmonary hypertension, adult respiratory distress syndrome, etc.; 8) Kidney: proteinuria, hematuria, tubuluria, nephrotic syndrome and renal function 9) digestive system: abdominal pain, diarrhea, nausea, vomiting, peritonitis and pancreatitis; 10) mesenteric vasculitis, protein-losing enteropathy or pseudo-intestinal obstruction are serious complications of digestive system involvement, with symptoms including fever, nausea, vomiting, diarrhea or bloody stools, abdominal pressure pain and rebound pain; 11) lupus eye involvement, with retinal 11) Lupus ocular involvement, with retinal lesions common, manifested as “cotton wool spots”, followed by keratitis and conjunctivitis; it may manifest as blurred vision, decreased visual acuity, eye pain and blackness.