Enteritis is usually accompanied by varying degrees of pain. Enteritis is mostly seen in small bowel inflammation, colitis, and proctitis caused by various pathogenic microorganisms such as bacteria, fungi, and viruses. The degree and nature of abdominal pain caused by enteritis of different causes and locations generally varies. The most common site of abdominal pain in patients with acute enteritis is usually around the umbilicus, i.e., the location of the small intestine. In the case of enteritis caused by Shigella infection, the site of abdominal pain is usually in the left lower abdomen, where the sigmoid colon and rectum are located. In addition, in mild cases of enteritis, there may be no pain or abdominal discomfort; in moderate cases, the pain may be mildly distending or stabbing, and in severe cases, the pain may be severe and may be accompanied by a sensation of falling. The abdominal pain is often paroxysmal and recurrent, and is usually relieved after defecation. Patients with severe pain can take medication under the guidance of a doctor, including drugs to relieve intestinal spasm, such as scopolamine and atropine, drugs to protect the gastrointestinal mucosa, such as enteritis, and antibacterial drugs, such as levofloxacin, but not painkillers for abdominal pain. Patients with severe abdominal pain are still advised to go to the hospital as soon as possible to avoid serious complications.