According to NCI version 3.0 grading criteria, rashes are classified into 5 grades. Grade 1: spots, papules, erythema without concomitant symptoms Grade 2: spots, papules, or erythema with concomitant symptoms such as pruritus, localized desquamation or other damage area <50% Grade 3: severe and widespread erythema or spots, papules, herpes, desquamation area >50% Grade 4: widespread epidermal exfoliation, ulcerative maculopapular dermatitis Grade 5: death Grading of acneiform rash Mild: confined to the head and upper trunk, almost No subjective symptoms, no effect on daily life, no secondary infection Moderate: more extensive, mild subjective symptoms, slight effect on daily life, no signs of secondary infection Severe: extensive, severe subjective symptoms, greater effect on daily life, possibility of secondary infection Preventive treatment: From the beginning of treatment, use alcohol-free emollient lotion to apply to the skin, reduce sun exposure, use anti-wren on exposed skin II rash treatment recommendations: mild: no treatment required or topical use of topical application of 1% hydrocortisone ointment or chlorine cotrimoxazole (10%), erythromycin ointment, dry semi-pruritic skin, thin phenol glycerin lotion Bid or benadryl ointment applied itchy local Moderate: topical application of 2.5% hydrocortisone ointment or erythromycin ointment or urea ointment. Severe: In addition to topical creams to add shock doses of methylprednisolone and oral cefuroxime to be evaluated after two weeks. Chinese medicine: According to the research and treatment experience of Sichuan Cancer Hospital, Jinyinhua can be given 10-15 grams of decoction for external application and oral intake, 2/day.