Adults with fever in the middle of the night need to measure the body temperature first, and then take appropriate methods to reduce fever according to the temperature situation. If the body temperature is below 38.5 ℃, you can use physical cooling methods to reduce fever, as follows: 1, drink more water: a small number of times to drink warm water, not only to replenish the liquid, but also to speed up sweating, urination, and promote the body’s toxins and metabolic waste discharge; 2, alcohol wipe: 75 percent of alcohol 100ml, plus 27-30 ℃ warm water equal amount, using a towel from the neck to wipe, from 3.Ice bag cold compress method: put an appropriate amount of ice into an ice bag, add an appropriate amount of water, wrap a towel around the outside and place it on the patient’s forehead for 15 minutes; 4.Wet towel compress method: wring a towel soaked in cold water to half dry and put it on the patient’s forehead or armpit, groin and other large blood vessel parts to achieve the purpose of cooling. If the fever cannot be reduced by physical cooling, or the body temperature is above 38.5℃, you can take ibuprofen, etc. to reduce the fever. If medication is still ineffective and the body temperature is high, it is recommended to seek medical attention in a timely manner to find the cause and give corresponding treatment.