Still’s disease in adults is a syndrome with a diverse clinical presentation. Almost all patients have a high fever, and most patients develop a rash during the course of the disease. 86% to 98% of patients may have joint pain, pressure, or arthritis, with 80% to 88% of patients having arthralgia on first presentation. 50% to 70% of patients have significant sore throat, especially early in the course of the disease (within the first month). Sore throat can be considered as a diagnostic manifestation. Other clinical manifestations are hepatosplenomegaly, lymph node enlargement, abnormal liver function and myalgia. A small number of patients have pulmonary and cardiac involvement. Neurological involvement is less common, with reports of meningoencephalitis and peripheral neuropathy, sensory neurological hearing loss, and focal central nervous system damage seen on MRI. Laboratory tests lack specificity. Lymph node biopsies show chronic nonspecific inflammation or reactive hyperplasia. Bone marrow cytology shows infected bone marrow picture. Recent studies have found elevated serum ferritin titers to be diagnostic for acute adult Still disease with a sensitivity of 69% and specificity of 29%. Decreased titers are a reliable indicator of effective treatment. Decreased glycated ferritin has a sensitivity of 83% and specificity of 69%, and the combination of the two has a sensitivity of 67% and specificity of 80%. The following diagnostic criteria can be referred to in the diagnosis of this disease: 1. Cush criteria: with the following 1 to 4 and two of a ~ d can be diagnosed, ① fever ≥ 39 degrees ② ② arthritis and/or arthralgia; ③ ③ rheumatoid factor (RF) negative; ④ ④ antinuclear antibody (ANA) negative; a. white blood cells ≥ 15 × 109 / L; b. rash; c. pleurisy or pericarditis; d. hepatomegaly or splenomegaly, or generalized lymph node enlargement. 2. Calabro criteria: ① peak fever (39°C or higher) without other causes, 1 to 2 peaks per day; ② arthritis, arthralgia or myalgia; ③ negative ANA and RF (standard method); ④ at least two of the following: rheumatoid rash, generalized lymph node enlargement, splenomegaly, a cardiopulmonary manifestation (pleurisy, pneumonia, pericarditis, myocarditis), neutrophil elevation (leukocyte count >15×109/L); ⑤ Exclude other causes of high fever, rash, arthritis, arthralgia. The diagnosis can be confirmed by meeting the above 5 criteria, otherwise it is only an experimental diagnosis. In terms of treatment, glucocorticoids have significant effect on fever, rash, joint pain, etc. Generally, sufficient amount of prednisone (1mg/kg/day) can control the disease quickly, and if necessary, equal amount of dexamethasone can be administered intravenously. After the symptoms are relieved, the hormone can be gradually reduced. The maintenance amount is 10-20mg/day for 2-3 months. We believe that giving non-corticosteroid anti-inflammatory drugs such as anti-inflammatory pain, ibuprofen or diclofenac is necessary to relieve symptoms and reduce hormone dosage. For those who do not have good results with the above treatment, we can consider performing methylprednisolone (1g/day for 3 days) or methotrexate (20-40mg, 1 time/week) or cyclophosphamide (800-1000mg, 1 time/2-4 weeks) shock treatment.