Hepatocellular carcinoma is one of the most common malignant tumors worldwide. Clinically, clinical diagnosis can be made by combining medical history, tumor marker tests and imaging examinations, but pathological examination after puncture or surgical resection is required to confirm the diagnosis. At present, the diagnosis of hepatocellular carcinoma can be confirmed by meeting any one of the following three criteria: hepatocellular carcinoma imaging, AFP abnormality and positive liver tissue biopsy.1. Hepatocellular carcinoma imaging: AFP (alpha-fetoprotein blood concentration) test value <400ng/ml, but with two typical hepatocellular carcinoma imaging (ultrasound, enhanced CT, MRI or selective hepatic arteriography) manifestations, i.e. a mass >2cm of occupying lesion. or patients with two positive liver cancer markers (DCP, GGT II, AFU and CAl9-9, etc.) as well as one imaging test with occupying lesions characteristic of liver cancer; 2. Abnormal AFP: AFP (alpha-fetoprotein blood concentration) test value ≥400ng/ml, along with one typical imaging manifestation of liver cancer, i.e., the lesion of occupying lesion >2cm, and during physical examination Patients with enlarged, hard and large nodular masses can be touched during physical examination; 3. Positive liver tissue biopsy: Patients with positive liver histopathological examination, i.e. liver tissue extracted by puncture for examination. Usually, patients with one of the above conditions can be diagnosed as liver cancer. After diagnosis, patients should further determine the size, spread and deterioration of cancer lesions, and then choose surgery, radiotherapy and chemotherapy under the guidance of doctors.