1.Pre-operative chemotherapy is equivalent to doing drug sensitivity test in the body in advance, which is helpful to understand the most suitable protocol for the patient’s physique. 2.Increase the success rate of breast conservation. 3.If preoperative treatment can kill the whole tumor, then the prognosis will be much easier. Another treatment option is “surgical resection”, that is, intraoperative rapid pathological diagnosis, and major surgery for malignant cases, this option is favored by primary and local hospitals. Nowadays, the mainstream international treatment view is to wait for the pathology results before treatment. For breast cancer, if it is not detected in time, it is usually a systemic disease as soon as it is detected, because the circulation and transportation of the body will lead to the presence of tumor cells all over the body, and even some malignant cells are already colonizing and growing, thus the earlier the systemic treatment is started, the more beneficial it is. Therefore, surgery can only control the local area, and even if the tumor is cut, it does not mean that everything is fine. For patients, since they decided to do preoperative chemotherapy, they should follow the standard procedure and should not suddenly switch to resection in the middle of the procedure. In fact, in general, as long as the protocol is effective and the body can tolerate it, it is recommended to complete all treatment cycles of the protocol before proceeding to other treatments. It may even be considered to complete all chemotherapy before surgery to achieve complete improvement of pathological symptoms before surgery, i.e. manifesting as tumor shrinkage on palpation, softening, change of tumor enhancement pattern under MRI enhanced scan, etc. The treatment itself is not based on what is primary and what is secondary, but is defined according to the specific situation of each individual and the different means of treatment at each stage, just as surgery is warfare and chemotherapy is economic sanction, all treatment is to achieve the purpose of winning. Rosie followed this treatment plan and survived the 5-year danger period after breast-conserving surgery and is still healthy.