Unless the condition is chronic, it is not recommended to take any medication before vaccination, especially note that glucocorticoids and immunosuppressive drugs cannot be taken, which suppress the body’s immunity and affect the production of antibodies after taking them, which can easily lead to immune failure. Therefore, vaccination is not recommended for patients taking immunosuppressive therapy. Patients with chronic diseases, such as diabetes, hypertension, coronary heart disease, chronic hepatitis B, etc., need to take medication for a long time. These drugs do not have the effect of lowering the immunity of the body, so there is no need to stop taking them, and the vaccination can be given according to medical advice if the condition is stable. If the patient is in the acute attack period of chronic diseases, or for patients with fever or acute diseases, it is recommended that vaccination be carried out after recovery. In general, vaccines need to be administered in a healthy state to reduce adverse reactions to the vaccine and to avoid aggravation of the original disease due to vaccination. If the vaccinated person is allergic, it is recommended to consult a doctor before vaccination to see if the vaccine is available to avoid serious allergic reactions.