Parkinson’s, also known as tremor palsy, is a common movement disorder in middle-aged and older adults. It manifests as resting tremor, bradykinesia, and myotonia. One of the most effective drug treatment is dopamine replacement therapy. The common drug is compound levodopa. Due to the specificity of the cause of the disease and the specificity of the drug, there are a lot of things to pay attention to and contraindications when taking this kind of drug. 1, three meals less protein food such as meat and dairy products. Because milk can be decomposed in the intestinal tract to produce a large number of amino acids, amino acids can hinder the absorption of levodopa in the intestinal tract, so that its efficacy is reduced. 2, the best time to take on an empty stomach is 30 minutes before a meal, followed by one hour before a meal or two hours after a meal. Because this kind of drug and food with the service will reduce the absorption rate. 3, prohibit calcium antagonists such as nifedipine a class of antihypertensive drugs. The antagonism between drugs reduces the efficacy of the drug.4. Acetylcholine is prohibited because Parkinson’s disease is due to hyperfunction of the acetylcholine system resulting in increased muscle tone, decreased movement, muscle tremor, so attention should be paid to the intake of acetylcholine drugs.5. Vitamin B6 is prohibited because vitamin B6 is a dopamine dehydroxylase coenzymes to improve the activity of the drug will promote the formation of dopamine outside the brain to reduce the amount of drugs into the central nervous system, and to reduce the dosage of the drug into the brain, and to reduce the dosage of the drug into the central nervous system. The amount of dopamine entering the central nervous system is reduced, thus decreasing the effectiveness of the drug.6. Gastrointestinal stimulants, such as morphine, are prohibited. Because gastrointestinal power drugs have the effect of blocking dopamine, promote gastric emptying, reduce the absorption rate. 7, glaucoma patients should be used with caution because dopamine is a kind of drug that can elevate blood pressure, has a certain effect on intraocular pressure, so you need to pay attention to changes in intraocular pressure during the medication.