In fertility clinics, we often get questions like, “Why is the treatment plan so different when she and I have the same infertility?” “Can I also use my friend’s previous prolotherapy program?” In the face of such questions, we would like to talk to our patients about the common ovulation protocols. In vitro fertilization ovulation promotion, clinically known as controlled ovulation promotion, through the controlled administration of drugs to the pituitary gland and ovaries, to achieve the purpose of simultaneous growth and development of multiple follicles, as each patient’s ovarian function is different, therefore, there are various ovulation promotion protocols, this article introduces the common long protocol and short protocol (ultra-short protocol) to the majority of patients. The long regimen, also known as the long luteal phase regimen, starts on day 21 of the patient’s menstrual cycle with the injection of gonadotropin-releasing hormone agonist, 0.1mg or 0.05mg per day for 14 days, the main effect is pituitary hyporegulation, the purpose of which is to desensitize the pituitary gland and make it dormant so that it does not interfere with the subsequent ovulation. It takes about 10 days, and when about 60%-70% of the follicles reach 17mm or more, the chorionic gonadotropin (HCG) injection can be given and the egg retrieval scheduled (usually 36 hours after HCG injection). The long protocol is the most common and classical one in IVF ovulation promotion and is widely used due to its good controllability and high pregnancy rate. However, not all patients are suitable for the long regimen. For older patients with poor ovarian response or patients with few eggs from the previous long regimen, the long regimen may result in excessive pituitary suppression and poor response to ovulation, so we usually recommend the short or ultrashort regimen for these patients. Currently, our center is using the ultra-short regimen for patients with poor ovarian function. Injections of gonadotropin-releasing hormone agonist 0.1 mg are given from the second day of menstruation, usually for about 3-4 days, mainly using the early stimulation effect of gonadotropin-releasing hormone agonist on the pituitary gland for the purpose of follicle recruitment. The application of gonadotropin to promote follicle growth is started at the same time from the 3rd day of menstruation for about 8-10 days, and again when about 60-70% of the follicles reach 17mm or more, it is time to inject chorion of chorionic gonadotropin (HCG) and schedule the egg retrieval. Since the ovarian function of each patient is different, the suitable ovulation protocol is not the same, and it is not the best one.