Proliferative osteoarthropathy is a chronic joint disease caused by degenerative changes in the joints that result in the destruction of joint cartilage. It is also known as degenerative arthritis, osteoarthritis and hypertrophic arthritis. Bone growth in the joints of middle-aged and elderly people is called proliferative osteoarthritis or proliferative osteoarthropathy, which is a manifestation of degenerative bone changes. The causes of osteophytes in the joints of the middle-aged and elderly are: 1. Long-term, chronic wear and tear of the joints can cause damage to the bone and cartilage of the joints to varying degrees, and the repair of the damage is often manifested as abnormal bone or cartilage hyperplasia. 2, the joint parts of the change in the state of stress, middle-aged and elderly people due to the decline in muscle strength, ligament flexibility, physical changes (such as obesity) and changes in walking habits, can make the joint (especially the hip joint, knee joint) on the state of change in stress. Such as walking on one side of the joint force soft large, while the other side of the force soft small, long-term, the greater force on the part of the inevitable phenomenon of osteophytes. 3, endocrine changes: With the increase of age, the hormones in the body of the elderly, especially the level of sex hormones have changed significantly and these hormones are directly related to bone metabolism. When the endocrine changes, it will inevitably lead to changes in the bones and the phenomenon of osteoporosis or hyperplasia.