There are more types of proctitis and not all of them need to be treated with Mesalachin suppositories, which can treat mild or moderate ulcerative proctitis in proctitis. Mesalachin is often considered the drug of choice for mild to moderate ulcerative proctitis and Crohn’s disease. It is available in tablet and suppository form and can be used to treat both ulcerative proctitis and Crohn’s disease if the site of origin is in the rectum or sigmoid colon. In addition to ulcerative proctitis, proctitis also includes infectious proctitis and radioactive proctitis, etc. The therapeutic effect of Mesalachin suppositories is more general for the above-mentioned types of proctitis. In addition, if the proctitis is caused by ischemic enteropathy, the pathogenesis of which is the occlusion of the blood vessels that govern the rectum, causing erosion and necrosis of the rectal mucosa and leading to proctitis, this type of proctitis needs to be treated with drugs that invigorate blood stasis and unblock blood vessels, rather than using Mesalachin suppositories. There are other non-specific inflammatory conditions causing proctitis that do not need to be treated with Mesalachin suppositories, but often need to be treated with probiotics. It should be noted that Mesalachin suppositories are contraindicated in patients with hypersensitivity to salicylates or their metabolites; caution in patients with liver and kidney dysfunction and asthma; contraindicated in young children; and lactating women need to stop breastfeeding while taking the drug.