Auditory neuroma is a benign intracranial tumor that develops slowly. The main clinical manifestations are cerebellopontocerebellar horn syndrome, including cranial nerve dysfunction dominated by vestibular nerve, cochlear nerve, trigeminal nerve and facial nerve, cerebellar damage symptoms, long conduction bundle damage symptoms and intracranial pressure increase symptoms. The emergence and development of clinical symptoms of auditory neuroma are influenced by many factors, such as tumor starting location, development direction, tumor size and blood supply. Patients may experience vertigo, tinnitus, hearing loss, nausea and vomiting. Especially, tinnitus and hearing loss can last for a long time without being noticed by the patient. If patients seek medical attention for dizziness or mild tinnitus at this time, they are often misdiagnosed as otogenic vertigo or neurogenic deafness. The growth of tumor in the internal auditory canal may compress the internal auditory artery and cause ischemic lesion in the cochlea, leading to the occurrence of sudden deafness. (2) Stage of tumor adjacent to cranial nerve damage: With the continuous development of tumor, the upper part of the tumor may reach the trigeminal nerve. If the sensory root of trigeminal nerve is stimulated, it may cause facial pain; if the sensory root is destructively damaged, it may cause facial hypesthesia and hypoacusis or loss of corneal reflex. Involvement of the motor roots of trigeminal nerve may cause ipsilateral masticatory muscle weakness, ipsilateral masticatory muscle and glabellar muscle atrophy. As the tumor continues to develop, the abducens nerve may be affected by the tumor in some patients, and patients may experience diplopia. In the process of growth, auditory nerve sheath tumor may push and pull the facial nerve, resulting in peripheral facial palsy and loss of taste sensation in the anterior 2/3 of the ipsilateral tongue to varying degrees. If the tumor continues to develop upward, it may cause ipsilateral extraocular muscle paralysis, pupil dilatation and loss of light reflex due to the strain on the nerve. Damage to the linguopharyngeal nerve, vagus nerve and parasympathetic nerve may cause dysphagia, choking and coughing, loss of taste sensation in the posterior 1/3 of the ipsilateral tongue, soft alligator palsy, hoarseness, loss of ipsilateral pharyngeal reflex and paralysis or atrophy of sternocleidomastoid muscle and trapezius muscle. (3) Compression stage of brainstem and cerebellar structures: the tumor can push out the brainstem when it develops medially, and when the tumor is huge, it can cause the dysfunction of conduction bundle in the brainstem, and the patient will have different degrees of hemiparesis and hemianopsia of the contralateral limbs. Sometimes, patients may experience hemiparesis and hemianesthesia on the affected side or bilaterally. The displacement of the brainstem may cause the strain on the oculomotor nerve, resulting in unilateral or bilateral oculomotor nerve damage and eye movement disorder, eyelid ptosis, pupil dilatation and other symptoms. The prolonged compression of cerebellar peduncle and cerebellar hemispheres by tumor may lead to ipsilateral limb ataxia, inability to judge distance correctly, cerebellar dysarthria and other symptoms. (4) Increased intracranial pressure stage: Patients will produce symptoms of increased intracranial pressure such as progressively aggravated headache, nausea, vomiting and optic papilloedema. Even some patients may suffer from secondary optic nerve atrophy due to prolonged cranial pressure increase, and even blindness in severe cases. The volume of posterior cranial fossa is small, and the compensatory ability to increase intracranial pressure is very limited. As the tumor keeps increasing, the cerebellar tonsils are pushed by the tumor and extend into the cervical spinal canal, which is in the state of chronic lower herniation, reflexively causing the patient’s neck stiffness, posterior cervical pain and discomfort and posterior occipital pain. In addition, the stimulation of local dura mater and other structures by tumor can produce local pain in suboccipital area. In the advanced stage of the disease, the patient may even have impaired consciousness and may have coracoacusis-like rigidity attack. (2) Stages of development of auditory neuroma and corresponding symptoms: (1) Early stage: When the diameter of tumor is <2.5cm, it is the early stage of auditory neuroma. As the tumor compresses the cochlear and vestibular branches of the auditory nerve in the internal auditory canal, the early symptoms are mostly tinnitus, hearing loss, vertigo, gait instability and other symptoms of cochlear and vestibular dysfunction, but sudden deafness can also be seen (about %). One or more of these common early symptoms may be present, or they may occur simultaneously. The frequency and severity of symptoms vary from person to person, and may go unrecognized in mild cases to interfere with daily life due to recurrent episodes of vertigo or persistent gait instability in severe cases. Rare early symptoms include itching or tingling in the ear, numbness in the posterior wall of the external auditory canal, and reduced tearing on the affected side due to pressure on the median nerve in the internal auditory canal. (2) Middle and late stage symptoms: With the increasing of tumor, the symptoms gradually aggravate when. If the tumor extends to the pontocerebellar angle, it may involve the trigeminal nerve and cause abnormal sensation and numbness on the affected side, and the corneal reflex may be blunted or disappear; if the tumor obstructs the cerebrospinal fluid circulation, it may cause hydrocephalus and severe intracranial hypertension such as headache, nausea, vomiting and optic papilledema; if the tumor compresses the cerebellum, it may cause cerebellar dysfunction such as fine motor disorder of the affected side, unstable walking gait, etc.; if the tumor compresses the brainstem, it may cause Tumor compression of brainstem may lead to numbness and sensory loss of limbs. If the tumor enlarges to a certain extent, it may cause headache, nausea, vomiting and other symptoms due to the increase of intracranial pressure, and the patient may die due to sudden brain herniation.