One of the common causes of female infertility is uterine infertility. According to our clinical observations, endometrial adhesions are the most important of these causes. How do endometrial adhesions occur? We know that the normal female endometrium is divided into a functional layer and a basal layer. The basal layer is close to the myometrium and contains “endometrial stem cells” that can proliferate and differentiate into functional endometrial cells under a specific sex hormone environment. The functional layer, in turn, undergoes regular changes of proliferation => secretion => exfoliation with the regular fluctuation of sex hormones during the menstrual cycle, which is often referred to as the menstrual cycle. When certain pathogenic factors influence the endometrium, such as microbial infection, mechanical destruction of the endometrium (e.g. abortion) to the basal layer, irreversible damage to the endometrium results because the damaged area no longer has the ability to differentiate and compensate for the missing functional layer. As a way for the organism to heal the damage, endometrial adhesions then occur. From the above, since endometrial adhesions are caused by irreversible damage to the endometrium, this irreversibility, no matter how it is treated, can theoretically no longer be reversed. Therefore, even if these adhesions are separated using medical methods, eventually the organism still has to choose to re-adhere as a way of bridging the damage. So are endo-adhesions really that difficult to treat? No, not really. Even when irreversible damage to the endothelium occurs, it is often focal, like an oasis in a desert. After separating the foci of endometrial adhesions and preventing the adhesions artificially for a period of time by means of intrauterine devices, the endometrium is promoted to fully proliferate and secrete through reasonable sex hormone therapy, and the “endometrial stem cells” around the foci are differentiated to make up for the missing stem cells at the foci to a certain extent, so as to reduce the scope of adhesions and mitigate the degree of adhesions. The purpose is to reduce the extent and degree of adhesions. This improvement cannot be achieved overnight, but may require several hysteroscopies, adhesions disintegration, and sex hormone therapy. Although the whole process may be long and difficult, it may be the only reliable treatment for endometrial adhesions until the clinical application of endometrial stem cell transplantation is completely resolved.