At present, the targeted drugs for the clinical treatment of small cell lung cancer, third-line drugs: multi-targeted anti-angiogenic drugs, such as Anrotinib, but small cell lung cancer is more sensitive to radiotherapy, and clinically, chemotherapy is mostly adopted with radiotherapy for treatment. There are very few targeted drugs for the treatment of small cell lung cancer, and the commonly used one in clinic is Anrotinib, which is suitable for the treatment of patients with locally advanced or metastatic non-small cell lung cancer who have progressed or relapsed after receiving at least two systemic chemotherapies before. Under normal circumstances, small cell lung cancer is more sensitive to chemotherapy, so the treatment is usually based on chemotherapy, and etoposide, cisplatin and other drugs are mostly used in clinic for treatment, and it can also be combined or sequential radiotherapy. During the period of treatment, one should pay attention to avoiding labor, regular work and rest, avoiding infection, and eating more fresh vegetables and fruits to replenish nutrients for the body. Which kind of treatment for small cell lung cancer should listen to professional doctor’s advice and use medicine under doctor’s guidance to avoid adverse situation.