The most common arrhythmia associated with heart valve disease mitral stenosis is atrial fibrillation. When mitral stenosis occurs, blood from the left atrium cannot enter the left ventricle smoothly when the heart is in diastole. In the long run, the burden on the left atrium is getting bigger and bigger, which leads to atrial dilatation and myocardial remodeling, and in the process of myocardial remodeling, the atrial conduction system will be remodeled together, and the remodeled conduction system is prone to cause all kinds of cardiac arrhythmia, and one of the most common ones is atrial fibrillation. When atrial fibrillation occurs, patients may experience symptoms such as palpitations, chest tightness, dizziness, and fatigue. If organic heart disease exists, atrial fibrillation can induce angina pectoris and heart failure. Atrial fibrillation causes blood to stagnate in the atria, which can easily lead to thrombosis, and thrombus dislodgement can cause thromboembolism when it runs with the blood circulation. Some patients do not have any clinical symptoms and only have abnormalities when an electrocardiogram is performed. When mitral stenosis is detected, it is important to go to a regular hospital and take timely measures to avoid myocardial remodeling.