Regenerative medicine is currently an emerging discipline that uses human embryos, mature tissues and organs to treat diseases and clinically applied drugs that have not yet been solved. Stem cells are a class of undifferentiated, pluripotent cells with certain characteristics. They have the potential to differentiate into multiple cells, can expand exponentially in vivo and have immunological properties. Because of their powerful properties, stem cells are very effective in the treatment of neurological disorders such as multiple sclerosis, diabetic neurological complications and post-stroke recovery. The existence of endometrial stem cells has been suggested by Prianishinikov in 1978 and confirmed by Padykula et al. These cells were identified by the side-population cell technique. Although the existence of endometrial stem cells has been demonstrated for almost 30 years, their medical exploration began in the last few years. patients. In this experiment, they injected anhydrous ethanol into the uterine cavity of rats to establish an endometrial thinning model. The rats were randomly divided into three groups: experimental group – intravenous injection of bone marrow stem cells, control group – intravenous injection of saline, and blank group – normal rats without any treatment. Nagori et al. reported on the use of stem cells in the treatment of young infertile patients with severe uterine adhesions accompanied by endometrial thinning. The autologous bone marrow was infused into the uterine cavity after endometrial scraping and then the application of estradiol was continued, most likely increasing the endometrium to 8 mm and pregnancy after embryo transfer. Gargett and Healy wondered if the bone marrow stem cells implanted into the uterine cavity differentiated into endometrial epithelial cells, stromal cells or vascular cells in the successful case mentioned earlier. Or did the bone marrow stem cells secrete nutritional factors that promote angiogenesis, prevent endometrial cell apoptosis and secrete growth factors to induce endometrial stem cell proliferation? Or is it the activation of regeneration of existing endometrial stem cells through diagnostic scraping to promote endometrial repair? These cutting-edge and inspiring technical tips play a crucial role in regenerating and repairing stem cells in thin endometrium endometrium with great hunger, and stem cell therapy is very therapeutic potential for patients for whom conventional treatment for thin endometrium has not been effective. However, for those patients with thin endometrium who do not respond to conventional treatments, more in-depth studies are needed to clarify the role of stem cells, the dosage, the therapeutic route and the appropriate treatment regimen.