IgG is immunoglobulin G, a marker of distant viral infection, and is generally checked with IgM to determine the presence or absence of viral infection and the duration of infection. 1, such as IgG positive, IgM negative, suggesting a long time ago infected with rubella virus, vaccination against rubella can also occur, rubella virus IgG has a certain degree of protection, which can reduce the possibility of patients infected by rubella virus. 2, such as IgG positive, IgM positive, suggesting a recent infection with rubella virus, unsuitable for pregnancy, such as already pregnant, it is recommended to improve the pregnancy test to screen for possible pediatric malformations. 3, If IgG and IgM are negative, it suggests that you have never been infected with rubella virus, or you have been infected with rubella virus, but time has passed and IgG has been depleted, you can get rubella vaccination if you have a pregnancy plan, if you are already pregnant, you must strictly prohibit rubella vaccination (live vaccine, which has some toxicity and may directly cause rubella). 4. If the IgG is negative and the IgM is positive, it indicates a recent (within a week) infection with rubella virus, IgM has been formed but not yet IgG, and the treatment is the same as 2. Rubella virus and other viral series are important screening indicators in early pregnancy, and understanding the significance of various indicators is beneficial in assessing the risk of malformed children.