In the course of clinical treatment therapy, we learned that many patients and their families were misled to believe that blood-activating and stasis-transforming traditional Chinese medicines such as Andrographis paniculata, safflower, trigonella and curcuma would cause tumor spread. In fact, this is typical of using the rigid Western medical thinking to understand Chinese medicine out of context, thus confusing and misleading the patients. On the contrary, most of the herbal medicines that activate blood circulation and remove blood stasis have good therapeutic effects on tumors, not to mention causing tumor proliferation and recurrence. I would like to write an article to set the record straight, to clear the name of these herbs, and to give a brief account of their anti-tumor efficacy, to shout for them. If the qi and blood do not run smoothly, blood stasis will accumulate in the body with phlegm and other pathogenic factors, which will lead to tumors, that is, cancer. Blood stasis is one of the causes of tumor, and the treatment should be the right medicine. Therefore, the method of activating blood stasis and removing blood stasis is a common clinical treatment for tumor. Therefore, the method of activating blood and removing blood stasis is a common clinical treatment for tumors. The method of activating blood and removing blood stasis can not only eliminate evil and eliminate tumors to treat tumors, but also can be used in combination with other methods to treat fever caused by blood stasis, bleeding caused by blood stasis and pain caused by blood stasis in meridians. This is the root of the treatment. “To treat a disease, we must seek the root”. The mechanism of action of blood-stasis activating drugs against tumor and its malignant metastasis 1, affect malignant tumor cell oncogene expression; 2, directly inhibit and kill tumor cells; 3, induce apoptosis of tumor cells; 4, induce differentiation of tumor cells; 5, inhibit telomerase expression; 6, block tumor vascular formation; 7, improve the body’s immune function; 8, have a potentiating and reducing effect on radiotherapy; 9, improve blood rheology, eliminate microcirculatory disorders, etc. The Chinese medicine leech, commonly known as leech, its extract leechin has the effect of activating blood circulation, relieving spasm, softening and reducing tumor. Modern medical research shows that hirudin is a powerful anticoagulant that can significantly reduce blood viscosity, neutralize thrombinogen, counteract ADP-induced thrombosis, dilate blood vessels and relieve arterial spasm. The high anticoagulant effect of hirudin is very conducive to the entry of anticancer drugs into tissues to kill tumor cells, and therefore has a facilitating effect on radiotherapy. “Qingcheng is the most secluded place in the world, and the first cave in western Sichuan. Where the immortal cranes pass by, good medicine descends to the sky”. This is the Chuanxiong Ligusticum that Sun Simiao, the king of medicine, spoke of. Its active ingredient, Chuanxiong Ligusticum, can improve the blood hypercoagulable state and the internal environment where malignant tumors exist, exerting an anti-tumor metastatic effect, which is very beneficial to tumor treatment. Danshen is a commonly used drug in Chinese medicine, and it has been compared to “one flavor of Danshen, which is the same as four things”, which means “four things soup” (composed of Angelica sinensis, Dihuang, Chuanxiong and Bai Shao). The “Four Materia Medica” has the function of nourishing the blood and invigorating it, while one flavor of Salvia is equivalent to the effect of four medicines, which shows the wonderful use of Salvia. Pharmacological studies have confirmed that Salvia miltiorrhiza can improve the hypercoagulable state of blood by promoting fibrinolysis, inhibiting platelet aggregation, improving microcirculation and reducing blood viscosity, degrading the new capillaries in tumor metastases and improving their immunity. There are many other herbs commonly used to activate blood circulation and remove blood stasis, which can be regarded as a large number of soldiers. For example, Andrographis paniculata, Panax notoginseng, Safflower, Yujin, Yuanhu, Boswellia, Myrrh, Wu Lingliao, Wang Bu Liu Xing, Whole worm, Centipede, Zang Fang, Water safflower seeds, Shi Jian Dian Dian, Blood exhaustion and so on. These drugs, either used alone or in group formulas, have shown good therapeutic and preventive effects on tumors. With the development of medicine, blood-activating and stasis-transforming herbs will surely shine and shine in the position of anti-tumor and protect people’s life and health.