The performance of major depression mainly includes mood disorders, thought disorders, will activity disorders, cognitive dysfunction and pleasure deficits, etc. It is recommended that patients with depressive symptoms that cannot be self-relieved seek medical treatment in a timely manner, and can mostly be relieved or return to normal life status after active treatment. Do not feel the meaning of life, some patients’ depressed mood is more serious in the morning and less in the evening. Most of the patients with major depression are silent and talk little, or cry because of the pain inside, a few of them will suppress the pain inside and smile, the risk of suicide is higher in these patients; 2. In addition, patients with major depression have pessimistic and negative thinking, extremely low self-evaluation, feeling confused about the future, often suspecting that they are suffering from diseases, and may blame themselves for no reason, believing that their existence affects others, thus generating suicidal thoughts; 3, will activity disorder: major depression is often manifested as slow behavior, reluctance to contact and interact with people, distant from friends and relatives, or bedridden all day, do not want to work or go out, and in severe cases, even 4. cognitive dysfunction: patients with major depression often have reduced memory, or remember only pessimistic and negative things, and also have reduced attention and learning ability; 5. pleasure deficit: patients cannot experience pleasure from daily life activities, and there are some psychological symptoms, including delayed thinking, cognitive impairment, negative cognitive patterns, self-blame Self-guilt, often suicidal ideas and behaviors, anxiety, sleep disorders, insomnia and early awakening, panic and palpitations, eating disorders, decreased energy, and decreased sexual function; 6, Other: Some physical symptoms may also occur, such as insomnia, loss of appetite, weight loss, decreased sexual desire, amenorrhea, impotence, and pain in a certain part of the body.