Granulation after hemorrhoid surgery may be normal or it may be related to infection. Growing granulation after hemorrhoid surgery is generally not a cause for concern and may be normal. Granulation tissue in the process of tissue damage repair can resist infection, protect the wound, fill the defect, mechanization or wrapping necrosis, inflammatory exudate and so on. Eventually the granulation tissue matures into fibrous connective tissue and transforms into scar tissue. If granulation tissue overgrowth is abnormal, it may be due to contamination of the wound with fecal material leading to infection, which is characterized by prominent granulation tissue that bleeds easily, exudes more fluid, is friable, and rises above the level of the surrounding skin. Granulation tissue hyperplasia is often associated with an abnormal inflammatory response. The overgrowth of granulation tissue can affect the healing of the incision, and it is recommended to see a doctor for examination and treatment. If there is any discomfort, it is recommended to go to the hospital immediately for examination and follow the doctor’s instructions for treatment.