There are many causes of chest tightness and breathlessness in patients. When the ambient air pressure is low, or when the patient cries with great mental stimulation, symptoms such as labored breathing, chest tightness, and breathlessness can occur. In addition, heart disease, respiratory disease and other disease factors can also cause chest tightness, breathlessness and other symptoms. 1, heart disease: such as coronary heart disease, angina attack, heart failure, heart attack, congenital heart disease, rheumatic heart valve disease, pericarditis and hypertension patients with poor blood pressure control, may cause chest tightness and breathlessness and other symptoms occur. Patients with coronary artery disease may induce angina pectoris due to myocardial ischemia. In addition to chest pain, patients may also experience chest tightness and decreased activity endurance. If patients have sudden onset of chest tightness, chest pain, dyspnea, etc. during exertion, emotional excitement or exercise, they should be highly suspected of having angina pectoris and need further examination; 2. Respiratory system diseases: It may be due to the decline of lung function, resulting in patients’ ventilation and gas exchange disorders, which leads to symptoms such as dyspnea and shortness of breath. Common clinical diseases include chronic obstructive pulmonary disease, interstitial lung disease, bronchial asthma, bronchiectasis, severe lung infection, wheezing bronchitis, and pneumothorax, etc. Patients mainly present with dyspnea, which may occur with coughing, coughing and wheezing. This can be further improved blood gas analysis, chest CT and lung function and other related examinations to clarify the cause; 3, psychological diseases: common are anxiety, depression and cardiac neurosis and other related diseases, patients can appear chest tightness, breathlessness and other symptoms. Patients are advised to visit the psychology department to seek guidance and treatment from a psychiatrist; 4. Other: for example, myasthenia gravis, which may cause respiratory muscle paralysis or even laryngeal muscle relaxation and weakness, all of which may lead to symptoms such as self-conscious chest tightness and breathlessness. Or anemia, chronic renal insufficiency, liver cirrhosis, pesticide poisoning, and imbalance of acid-base balance and fluid metabolism may also manifest as symptoms of chest tightness and shortness of breath in different degrees.