There are many causes of pain in the middle of the chest, which can be broadly divided into non-organic diseases and organic diseases. Organic diseases generally include cardiogenic diseases, digestive system diseases and respiratory system diseases, etc.: I. Non-organic diseases: Non-organic diseases are commonly affected by the patient’s emotions, such as the presence of anxiety, depression, etc. These people may have chest tightness, chest pain and palpitations. The location of chest pain is usually not fixed, it may be located in the middle of the chest, or in the left anterior chest or right anterior chest, and the duration also varies, and the symptoms are multiple or last for a long time, to be distinguished from organic diseases. Second, organic diseases: 1. Cardiogenic diseases: The common cause of middle chest pain is cardiogenic diseases, such as angina pectoris, and patients may experience chest tightness and chest pain during exertion and activity. The chest pain can be located in the left precordial region or in the posterior or middle and lower sternum, lasting from a few minutes to more than 10 minutes, and can be relieved by rest or nitroglycerin. In addition, such as hypertension and cardiomyopathy may also cause pain in the middle of the chest; 2, digestive system diseases: In addition, digestive system diseases may also cause pain in the middle of the chest, such as reflux esophagitis, gastric ulcer, etc., mostly related to eating and hunger, gastroscopy is feasible for further clarification; 3, respiratory system diseases: Respiratory system diseases may also involve the chest lesions, such as pneumothorax or lung Pneumothorax or lung occupancy, etc., may stimulate the pleura and produce pulling pain. Abnormalities in the mediastinal area, such as mediastinal abscesses or mediastinal tumors and other diseases, may also cause pain in the middle part of the chest; 4, other: when there is pain in the middle of the chest, also pay attention to the presence of local spinal, skeletal and muscular abnormalities, such as intercostal neuralgia, chondromalacia, etc., as well as entrapment aneurysms, sudden tearing of the aorta, etc. can occur in the middle of the chest pain.