Percutaneous spinal endoprosthesis is an internationally advanced surgical procedure for the treatment of spinal disorders such as lumbar spinal stenosis, lumbar spondylolisthesis, lumbar instability and thoracolumbar fractures. This technique guides the precise percutaneous implantation of the pedicle nail with the help of an image navigation system without disrupting the normal anatomy of the spine, reducing the occurrence of medically induced instability of adjacent segments. Compared with traditional open surgery, the minimally invasive technique has obvious advantages, including small intraoperative incision, less trauma and bleeding; better efficacy, less side injuries and lower reoperation rate; and quick recovery after surgery, which allows patients to get out of bed early and provides favorable conditions for functional exercise. The patient was admitted to our department for “lumbar spinal stenosis”, and after the whole department discussed the indication for surgery, our chief orthopedic surgeons Lei Zhongmin, Huang Minghua and Xu Fanping performed lumbar 4 plate decompression, lumbar 4-5 disc removal, percutaneous pedicle screw internal fixation and Cage intervertebral fusion on the patient. The surgeon made 2 small holes of 1.5 cm in diameter next to the patient’s lumbar spine on the healthy side, and the decompression incision on the affected side was about 100 px long. the operation time was shortened by about 40 minutes compared to the traditional operation time. Director Lei said that traditional posterior lumbar spine surgery requires a 10 to 12 cm long incision in the patient’s back, followed by layer-by-layer peeling of the paravertebral muscles and soft tissues to reveal the vertebral plates and synovial joints. This surgical approach is very damaging to the patient’s muscle tissue and the postoperative recovery time is very long. “It usually takes 10 to 14 days to be discharged from the hospital after surgery.” Director Lei said. In contrast, during minimally invasive surgery small holes are made in the patient’s muscle gaps and then the gaps are enlarged step by step with special equipment, so there is very little damage to the muscles and recovery is much faster than with traditional surgery. “Usually you can be discharged from the hospital in 3 days after surgery.” He said. In addition, traditional surgery takes a long time, exposes a large area, and bleeds more intraoperatively. “Usually patients have to transfuse 200ml to 600ml of blood,” said Director Lei. Minimally invasive surgery, on the other hand, does not require a blood transfusion after surgery because of the small incision, small damage and small amount of bleeding. The patient in this case was discharged from the hospital three days after surgery. The patient was very satisfied with the efficacy of the surgery and post-operative recovery.