First, first clarify the diagnosis of rheumatic diseases in the clinical hundreds of diseases, can be manifested as joint muscle swelling and pain, rash, weakness, fever and other symptoms, however, different rheumatic diseases in the treatment and prognosis are different, before treatment must be clearly diagnosed (i.e., confirm the diagnosis), so according to each of its different patients targeted laboratory tests, instrumentation and even biopsy pathological examination before a clear diagnosis. In fact, rheumatic diseases such as alveolar hemorrhage, acute interstitial pneumonia, acute nephritis, severe thrombocytopenia, hemophagocytic syndrome, acute hemolysis, acute mesenteric vasculitis, and central system lesions can be life-threatening within hours to days, so early identification is needed to gain valuable time for active treatment. Rheumatic diseases are autoimmune diseases, which can cause multi-organ and multi-system involvement. The prognosis and treatment plan are different in the same rheumatic disease due to different organ involvement. Therefore, it is necessary to assess whether there is damage to the kidneys, heart, whistle, nervous system, blood system, etc., before formulating different treatment plans. According to the patient’s symptoms, relevant tests (blood and urine routine, blood sedimentation, C-reactive protein, ferritin, complement, etc.), combined with different rheumatic activity scales, we can calculate the activity level of rheumatic disease and choose different treatment plans (including drug types and doses) according to the activity level. The treatment of rheumatism is based on its priority, activity and different organ damage, and other factors to develop a treatment plan, and then adjust the plan according to its treatment response and whether the patient has treatment-related adverse reactions, etc. The drugs are constantly increased or decreased by themselves. At the time of follow-up, make sure to bring medical history including outpatient medical records, discharge records, and labs to facilitate follow-up.